BPC-157
A 15-amino-acid peptide derived from human gastric juice that activates growth hormone receptors, promotes VEGF-driven angiogenesis, and restores structural integrity across connective tissues.
A 15-amino-acid peptide derived from human gastric juice that activates growth hormone receptors, promotes VEGF-driven angiogenesis, and restores structural integrity across connective tissues.
BPC-157 upregulates growth hormone receptor expression and stimulates VEGF-driven angiogenesis to accelerate vascular and tissue regrowth. It activates the FAK-paxillin pathway to promote fibroblast migration in tendons and ligaments, while modulating nitric oxide synthesis for enhanced blood flow. Its gastroprotective effects operate through prostaglandin pathways, offering systemic repair support.
- [1]Sikiric P, et al. (2018). Stable gastric pentadecapeptide BPC 157. Current Pharmaceutical Design, 24(18):1987-2000.
- [2]Chang CH, et al. (2011). The promoting effect of pentadecapeptide BPC 157 on tendon healing. Acta Histochemica, 113(7):651-660.
- [3]Gwyer D, et al. (2019). Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing. Cell and Tissue Research, 377(2):153-159.
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